Polymeric nanoparticles for protein kinase activity.
نویسندگان
چکیده
Nanoparticles were prepared from poly-ion complexes, possessing both PEI-FITC-(PKA-specific substrate) (kemptide) and PAA-TRITC, which produce intermolecular FRET; the nanoparticles were dissociated by phosphorylation, presented a strong FITC intensity and can be applied to high-throughput screening for large chemical libraries, for drug discovery of kinase inhibitors.
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عنوان ژورنال:
- Chemical communications
دوره 13 شماره
صفحات -
تاریخ انتشار 2007